Description: Use of Resealed Erythrocytes As Carriers and Bioreactors, Paperback by Magnani, Mauro (EDT); Deloach, John R. (EDT), ISBN 1461363217, ISBN-13 9781461363217, Brand New, Free shipping in the US Until recently the only biomedical use of erythrocytes was in transfusion medicine to restore a normal oxygen delivery. The development of a technology that permits one to open and reseal erythrocytes has dramatically changed this perspective. Currently, a number of teams have shown that engineered erythrocytes can behave as circulating bioreactors for the degradation of toxic metabolites or the inactivation of xenobiotics, as drug delivery systems, as carriers of antigens of vaccinal interest, and in many others biomedical applications. The technology of opening and resealing the erythrocytes has also been used successfully to investigate several basic aspects of erythrocyte metabolism, survival, pathology, etc. Thus, researchers in this field have an extraordinary opportunity to specifically modify the erythrocytes by the introduction of enzymes that generate new metabolic abilities, antibodies that inactivate single metabolic steps, or metabolites that can influence oxygen delivery and/or other cell properties. Furthermore, the pharmacokinetics of any drug can be potentially manipulated by using the erythrocytes as a delivery system. This book, The Use of Resealed Erythrocytes, is based on the fourth meeting of the "International Society for the Use of Resealed Erythrocytes as Carriers and Bioreactors" (I. S. U. R. E. ), held in Urbino, Italy, in 1991, and examines the most recent applications and developments of this technology.
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Book Title: Use of Resealed Erythrocytes As Carriers and Bioreactors
Number of Pages: Xiii, 361 Pages
Publication Name: Use of Resealed Erythrocytes As Carriers and Bioreactors
Language: English
Publisher: Springer
Publication Year: 2012
Subject: Biotechnology, Immunology, Life Sciences / Biochemistry
Type: Textbook
Item Weight: 25.4 Oz
Author: John R. Deloach
Item Length: 10 in
Subject Area: Science, Medical
Item Width: 7 in
Series: Advances in Experimental Medicine and Biology Ser.
Format: Trade Paperback
