Description: Tissue-Protective Cytokines Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Methods and Protocols Author(s): Pietro Ghezzi, Anthony Cerami Format: Hardback Publisher: Humana Press Inc., United States Imprint: Humana Press Inc. ISBN-13: 9781627033077, 978-1627033077 Synopsis While many cytokines are known for their inflammatory action, there is a growing interest in the tissue-protective effects of some cytokines. The prototypic tissue-protective cytokine is EPO. Initially described as neuro-protective, it is beneficial in animal models of ischemic and other types of injury. Scientists had to overcome the notion that EPO had only erythropoietic actions, was only produced by the kidney, and that its receptor was only present in erythroid progenitor cells. The use of in vitro and in vivo disease models was essential to demonstrate the protective effects of EPO. Reproducible models will be needed for the further study of the mechanism of action of EPO and for the identification of other tissue-protective cytokines. In Tissue-Protective Cytokines: Methods and Protocols, expert researchers in the field detail the key models that have been used to characterize the tissue-protective actions of cytokines. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, provide step-by-step laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Tissue Protective Cytokines: Methods and Protocols aids scientists in continuing to study tissue-protection that will be a new field of interest of cytokine biology, both in discovering novel actions of known cytokines and in developing new drugs.
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End Time: 2025-01-08T15:19:20.000Z
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Book Title: Tissue-Protective Cytokines
Number of Pages: 328 Pages
Language: English
Publication Name: Tissue-Protective Cytokines: Methods and Protocols
Publisher: Humana Press Inc.
Publication Year: 2013
Subject: Chemistry, Psychiatry
Item Height: 254 mm
Item Weight: 838 g
Type: Textbook
Author: Pietro Ghezzi, Anthony Cerami
Series: Methods in Molecular Biology
Item Width: 178 mm
Format: Hardcover