Description: Proteomics for Biological Discovery, Hardcover by Veenstra, Timothy D. (EDT); Yates, John R. (EDT), ISBN 1118279247, ISBN-13 9781118279243, Brand New, Free shipping in the US Building on the strength of the original edition, this book presents the state of the art in the field of proteomics and offers students and scientists new tools and techniques to advance their own research. Written by leading experts in the field, it provides readers with an understanding of new and emerging directions for proteomics research and applications. Proteomics for Biological Discovery begins by discussing the emergence of proteomics technologies and summarizing the potential insights to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are thoroughly covered, from underlying concepts to limitations and future directions. Later chapters provide an overview of the current developments in post-translational modification studies, structural proteomics, biochemical proteomics, applied proteomics, and bioinformatics relevant to proteomics. Chapters cover: Quantitative Proteomics for Differential Protein Expression Profiling; Protein Microarrays; Protein Biomarker Discovery; Biomarker Discovery using Mass Spectrometry Imaging; Protein-Protein Interactions; Mass Spectrometry Of Intact Protein Complexes; Crosslinking Applications in Structural Proteomics; Functional Proteomics; High Resolution Interrogation of Biological Systems via Mass Cytometry; Characterization of Drug-Protein Interactions by Chemoproteomics; Phosphorylation; Large-Scale Phosphoproteomics; and Probing Glycoforms of Individual Proteins Using Antibody-Lectin Sandwich Arrays. Presents a comprehensive and coherent review of the major issues in proteomic technology development, bioinformatics, strategic approaches, and applications Chapters offer a rigorous overview with summary of limitations, emerging approaches, questions, and realistic future industry and basic science applications Features new coverage of mass spectrometry for high throughput proteomic measurements, and novel quantitation strategies such as spectral counting and stable isotope labeling Discusses higher level integrative aspects, including technical challenges and applications for drug discovery Offers new chapters on biomarker discovery, global phosphorylation analysis, proteomic profiling using antibodies, and single cell mass spectrometry Timothy D. Veenstra, PhD, is the Director of the Laboratory of Proteomics and Analytical Technologies, Department of Applied Science, Maranatha Baptist University,Watertown, Wisconsin, USA. John R. Yates III, PhD, is in the Department of Molecular Medicine and Neurobiology, The Scripps Research Institute, La Jolla, California, USA.
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Book Title: Proteomics for Biological Discovery
Item Length: 10.1in
Item Height: 0.9in
Item Width: 7.2in
Author: John R. Yates III
Publication Name: Proteomics for Biological Discovery
Format: Hardcover
Language: English
Publisher: Wiley & Sons, Incorporated, John
Publication Year: 2019
Type: Textbook
Item Weight: 33.7 Oz
Number of Pages: 352 Pages
