Description: Genome-Scale Algorithm Design: Biological Sequence Analysis in the Era of High-Throughput SequencingVeli Mäkinen, Fabio Cunial, Alexandru I. Tomescu, Djamal Belazzougui Cambridge University Press Hardcover Unused and unread, cosmetic imperfections such as scuffs, creases or knocks. Stamped 'damaged' by publisher to a non-text page. EAN: 9781107078536 Published 07/05/2015 Language: English High-throughput sequencing has revolutionised the field of biological sequence analysis. Its application has enabled researchers to address important biological questions, often for the first time. This book provides an integrated presentation of the fundamental algorithms and data structures that power modern sequence analysis workflows. The topics covered range from the foundations of biological sequence analysis (alignments and hidden Markov models), to classical index structures (k-mer indexes, suffix arrays and suffix trees), Burrows–Wheeler indexes, graph algorithms and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualisations, exercises and problems, each chosen to reflect the steps of large-scale sequencing projects, including read alignment, variant calling, haplotyping, fragment assembly, alignment-free genome comparison, transcript prediction and analysis of metagenomic samples. Each biological problem is accompanied by precise formulations, providing graduate students and researchers in bioinformatics and computer science with a powerful toolkit for the emerging applications of high-throughput sequencing. Notation Preface Part I. Preliminaries 1. Molecular biology and high-throughput sequencing 2. Algorithm design 3. Data structures 4. Graphs 5. Network flows Part II. Fundamentals of Biological Sequence Analysis 6. Alignments 7. Hidden Markov models (HMMs) Part III. Genome-Scale Index Structures 8. Classical indexes 9. Burrows–Wheeler indexes Part IV. Genome-Scale Algorithms 10. Read alignment 11. Genome analysis and comparison 12. Genome compression 13. Fragment assembly Part V. Applications 14. Genomics 15. Transcriptomics 16. Metagenomics References Index. DispatchIn stock here - same-day dispatch from England. My SKU: 3196114RefundsNo-hassle refunds are always available if your book is not as expected.Terms and Conditions of SaleSorry - no collections. All sales are subject to extended Terms and Conditions of Sale as well as the Return Policy and Payment Instructions. Visit my eBay Store for details andmany more books. Template layout and design, "JNC Academic Books", "needbooks", Copyright © JNC INC. Designated trademarks, layouts and brands are the property of their respective owners. All Rights Reserved.
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Title: Genome-Scale Algorithm Design: Biological Sequence Analysis in th
ISBN: 1107078539
Pages: 413
Number of Pages: 413 Pages
Language: English
Publication Name: Genome-Scale Algorithm Design: Biological Sequence Analysis in the Era of High-Throughput Sequencing
Publisher: Cambridge University Press
Publication Year: 2015
Subject: Computer Science, Biology
Item Height: 253 mm
Item Weight: 960 g
Type: Textbook
Author: Alexandru I. Tomescu, Veli Makinen, Fabio Cunial, Djamal Belazzougui
Item Width: 180 mm
Format: Hardcover