E. coli in Motion by Howard C. Berg (English) Hardcover Book

Description: E. coli in Motion by Howard C. Berg Escherichia coli, commonly referred to as E. Scientists and engineers, not trained in microbiology, and who would like to learn more about living machines, can see it as a unique example. This cross-disciplinary monograph covers more than thirty years of research and is accessible to graduate students and scientists alike. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Escherichia coli, commonly referred to as E. coli, has been theorganism of choice for molecular genetics for decades. Its machineryand mobile behavior is one of the most fascinating topics for cellscientists. Scientists and engineers, not trained in microbiology,and who would like to learn more about living machines, can see it asa unique example. This cross-disciplinary monograph covers more thanthirty years of research and is accessible to graduate students andscientists alike. Notes This cross-disciplinary monograph covers more than 30 years ofresearch and is accessible to both graduate students and researchersalike. Scientists and engineers, not trained in microbiology, and whowould like to learn more about living machines will see this as aunique example. Back Cover The bacterium Escherichia coli - E. coli for short - has long been the organism of choice for unraveling biochemical pathways, deciphering the genetic code, learning how DNA is replicated and read, and even for manufacturing proteins of commercial interest. For some thirty years, it also has been a model for studying the molecular biology of behavior. E. coli swims in a purposeful manner, propelled by long thin helical filaments, each driven at its base by a reversible rotary engine. As a microscopic organism immersed in an aqueous environment, it has mastered physical constraints utterly different from any that we know, devising sensors, comparators, and motors on the nanometer scale. This cross-disciplinary monograph describes these feats in a manner accessible to scientists, engineers, and others not trained in microbiology who would like to learn more about living machines. It treats the history of the subject, the physiology, physics, biochemistry and genetics, largely from first principles. It is all about a small but remarkably sophisticated friend who lives in your gut. Topics discussed include: How does E. coli move about? How do cells decide whether life is getting better or worse? What is the machinery that makes this behavior possible? How is the construction of this machinery programmed? How does this machinery work? What remains to be discovered? Table of Contents Why E. coli?.- Larger Organisms.- Cell Populations.- Individual Cells.- Flagellar Motion.- Physical Constraints.- Optimal Control.- Cellular Hardware.- Behavioral Hardware.- Genetics and Assembly.- Gain Paradox.- Rotary Motor.- Epilogue. Review From the reviews:Physics Today, February 2005Review by Richard M. Berry, University of Oxford, UK"Howard Bergs book E. coli in Motion presents a classic example of interdisciplinary research at the interface between biology and physics, from 17th-century microscopy through major breakthroughs in the 1970s and 1980s, and up to the present. … Bergs book is well written and accessible yet densely packed with information and insight. … As one of the founders of the modern field of bacterial chemotaxis and an eminent figure in the world of biological physics, the author writes with authority. He presents E. coli not as the faceless biochemical factory familiar to geneticists and molecular biologists, but as an individual swimming around looking for food, making decisions, and trying to get along in the world. Often he invites the reader to step . . . into E. colis shoes, and he shows obvious affection for his tiny protagonist and for the process of scientific discovery. Yet, at the same time, the book gives a rigorous and essentially complete account of the field while touching on several relevant topics in molecular biology, physics, and biophysics. … E. coli in Motion is slim, and its short chapters are further divided into sections that are seldom more than a few pages long. Its style is concise and to the point. It brings simplicity and clarity in plain English to subject matter that might otherwise be complicated and difficult. The book is not short of colorful illustrations. … E. coli in Motion should appeal to a variety of readers. It is an excellently written and entertaining story of modern interdisciplinary science, full of information and without hype or wild speculation. For the specialist, it is a mine of information. But perhaps most of all, the book is a case study for anyone interested in the field of quantitative life science. I most heartily recommend it to anymathematician, physical scientist, engineer, or biologist who wants to learn more about what physics and biology can do for each other.""The book focuses on Escherichia coli, probably the best understood of all organisms … . Bergs book is well written and accessible yet densely packed with information and insight. … Its style is concise and to the point. It brings simplicity and clarity in plain English to subject matter that might otherwise be complicated and difficult. … should appeal to a variety of readers. It is an excellently written and entertaining story of modern interdisciplinary science … . I most heartily recommend it … ." (Richard M. Berry, Physics Today, February, 2005) Long Description The bacterium Escherichia coli - E. coli for short - has long been the organism of choice for unraveling biochemical pathways, deciphering the genetic code, learning how DNA is replicated and read, and even for manufacturing proteins of commercial interest. For some thirty years, it also has been a model for studying the molecular biology of behavior. E. coli swims in a purposeful manner, propelled by long thin helical filaments, each driven at its base by a reversible rotary engine. As a microscopic organism immersed in an aqueous environment, it has mastered physical constraints utterly different from any that we know, devising sensors, comparators, and motors on the nanometer scale. This cross-disciplinary monograph describes these feats in a manner accessible to scientists, engineers, and others not trained in microbiology who would like to learn more about living machines. It treats the history of the subject, the physiology, physics, biochemistry and genetics, largely from first principles. It is all about a small but remarkably sophisticated friend who lives in your gut. Topics discussed include: How does E. coli move about? How do cells decide whether life is getting better or worse? What is the machinery that makes this behavior possible? How is the construction of this machinery programmed? How does this machinery work? What remains to be discovered? Review Text From the reviews: Physics Today, February 2005 Review by Richard M. Berry, University of Oxford, UK "Howard Bergas book E. coli in Motion presents a classic example of interdisciplinary research at the interface between biology and physics, from 17th-century microscopy through major breakthroughs in the 1970s and 1980s, and up to the present. a? Bergas book is well written and accessible yet densely packed with information and insight. a? As one of the founders of the modern field of bacterial chemotaxis and an eminent figure in the world of biological physics, the author writes with authority. He presents E. coli not as the faceless biochemical factory familiar to geneticists and molecular biologists, but as an individual swimming around looking for food, making decisions, and trying to get along in the world. Often he invites the reader to astep . . . into E. colias shoes,a? and he shows obvious affection for his tiny protagonist and for the process of scientific discovery. Yet, at the same time, the book gives a rigorous and essentially complete account of the field while touching on several relevant topics in molecular biology, physics, and biophysics. a? E. coli in Motion is slim, and its short chapters are further divided into sections that are seldom more than a few pages long. Its style is concise and to the point. It brings simplicity and clarity in plain English to subject matter that might otherwise be complicated and difficult. The book is not short of colorful illustrations. a? E. coli in Motion Review Quote From the reviews:Physics Today, February 2005Review by Richard M. Berry, University of Oxford, UK"Howard Bergs book E. coli in Motion presents a classic example of interdisciplinary research at the interface between biology and physics, from 17th-century microscopy through major breakthroughs in the 1970s and 1980s, and up to the present. … Bergs book is well written and accessible yet densely packed with information and insight. … As one of the founders of the modern field of bacterial chemotaxis and an eminent figure in the world of biological physics, the author writes with authority. He presents E. coli not as the faceless biochemical factory familiar to geneticists and molecular biologists, but as an individual swimming around looking for food, making decisions, and trying to get along in the world. Often he invites the reader to step . . . into E. colis shoes, and he shows obvious affection for his tiny protagonist and for the process of scientific discovery. Yet, at the same time, the book gives a rigorous and essentially complete account of the field while touching on several relevant topics in molecular biology, physics, and biophysics. … E. coli in Motion is slim, and its short chapters are further divided into sections that are seldom more than a few pages long. Its style is concise and to the point. It brings simplicity and clarity in plain English to subject matter that might otherwise be complicated and difficult. The book is not short of colorful illustrations. … E. coli in Motion should appeal to a variety of readers. It is an excellently written and entertaining story of modern interdisciplinary science, full of information and without hype or wild speculation. For the specialist, it is a mine of information. But perhaps most of all, the book is a case study for anyone interested in the field of quantitative life science. I most heartily recommend it to any mathematician, physical scientist, engineer, or biologist who wants to learn more about what physics and biology can do for each other.""The book focuses on Escherichia coli, probably the best understood of all organisms … . Bergs book is well written and accessible yet densely packed with information and insight. … Its style is concise and to the point. It brings simplicity and clarity in plain English to subject matter that might otherwise be complicated and difficult. … should appeal to a variety of readers. It is an excellently written and entertaining story of modern interdisciplinary science … . I most heartily recommend it … ." (Richard M. Berry, Physics Today, February, 2005) Description for Sales People This cross-disciplinary monograph covers more than 30 years ofresearch and is accessible to both graduate students and researchersalike. Scientists and engineers, not trained in microbiology, and whowould like to learn more about living machines will see this as aunique example. Details ISBN0387008888 Author Howard C. Berg Short Title E COLI IN MOTION Language English ISBN-10 0387008888 ISBN-13 9780387008882 Media Book Format Hardcover Year 2003 Imprint Springer-Verlag New York Inc. Place of Publication New York, NY Country of Publication United States Birth 1934 DOI 10.1007/b11341;10.1007/b97370 AU Release Date 2003-10-01 NZ Release Date 2003-10-01 US Release Date 2003-10-01 UK Release Date 2003-10-01 Pages 134 Publisher Springer-Verlag New York Inc. Edition Description 2004 ed. Series Biological and Medical Physics, Biomedical Engineering Edition 2004th Publication Date 2003-10-01 Alternative 9781441918451 DEWEY 579.3 Audience Professional & Vocational Illustrations XII, 134 p. We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96312550;

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