Cytokines: From Basic Mechanisms of Cellular Control to New Therapeutics by Robe

Description: Cytokines: From Basic Mechanisms of Cellular Control to New Therapeutics by Robert Schreiber, Warren J. Leonard Cytokines (e.g., interleukins and interferons) are small signaling proteins that are essential for communication between cells. They are important regulators of the immune system, helping to control lymphocyte development and function, orchestrate inflammation, and defeat microbial and viral invaders. But they also play important roles in the nervous system, embryonic development, and diseases such as cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers the spectrum of cytokines that are produced and their roles in normal physiology and disease. The contributors examine the numerous cytokines and their cognate receptors, the downstream signaling mechanisms (e.g., JAK-STAT pathways) that mediate the effects of cytokines on cells, and the regulators that keep them in check (e.g., long noncoding RNAs and the SOCS and IRF protein families). These molecular interactions are discussed in the context of their physiological effects; the roles of cytokines in the development and activities of the immune system are emphasized. The authors also explore how the actions of cytokines may be modulated for treating patients with autoimmune disorders, immunodeficiency, infections, allergies, and cancer. Thus, this volume is an indispensable reference not only for cell biologists and immunologists but for all who are interested in targeting cytokine signaling for therapeutic purposes. FORMAT Hardcover LANGUAGE English CONDITION Brand New Author Biography Robert Schreiber is Professor of Molecular Microbiology at Washington University School of Medicine, St. Louis MO. Table of Contents Preface Structure of Cytokines J. Fernando Bazan IL-33 Alex Kallies and Ajithkumar Vasanthakumar GC Family Cytokines Warren J. Leonard Role of the Details ISBN1621821250 Series Perspectives Cshl ISBN-10 1621821250 ISBN-13 9781621821250 Format Hardcover Year 2018 Language English Edited by Leonard, Warren J. Imprint Cold Spring Harbor Laboratory Press,U.S. Place of Publication New York Country of Publication United States AU Release Date 2018-05-01 NZ Release Date 2018-05-01 UK Release Date 2018-05-01 Author Warren J. Leonard Publisher Cold Spring Harbor Laboratory Press,U.S. DEWEY 616.079 Illustrations Illustrations Audience General Pages 470 Publication Date 2018-05-31 US Release Date 2018-05-31 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:168359477;

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