Description: Title: Cell Type: Medical Journal Publisher: Cell Press / Cell Press Journals Frequency: Bi-Weekly Volume: 175 Issue Number: 3 Date Released: October 18, 2018 Features: ColorfulResourcefulInformative & Cutting-Edge Peer Reviewed Studies!Table of Contents: Leading Edge ■ ■ SELECT ■ ■ 601 ➥ First Encounters ➥ by J. Deguine ■ ■ PERSPECTIVE ■ ■ 605 ➥ Carbotoxicity--Noxious Effects of Carbohydrates ➥ by G. Kroemer, C. Lopez-Otin, F. Madeo, and R. de Cabo■ ■ REVIEW ■ ■ 615 ➥ Stem Cells, Genome Editing, and the Path to Translational Medicine ➥ by F. Soldner and R. Jaenisch■ ■ VOICES ■ ■ 633 ➥ Building a Better Brain■ ■ PREVIEWS ■ ■ 635 ➥ Human Cortical Dendrites: Stretched to Perform Better? ➥ by D. Dalugge and S. Remy637 ➥ Mixed Palettes of Melanopsin Phototransduction ➥ by M.T.H. Do639 ➥ Fear Extinction Requires Reward ➥ by S.A. Josselyn and P.W. Frankland641 ➥ Flipping ATP to AMPlify Kinase Functions ➥ by J.B. Sheetz and M.A. Lemmon ■ ■ SNAPSHOT ■ ■ 890 ➥ Biology of Genetic Ataxias ➥ by I. Eidhof, B.P. van de Warrenburg, and A. Schenck ■ ■ ARTICLES ■ ■ 643 ➥ Enhanced Dendritic Compartmentalization in Human Cortical Neurons ➥ by L. Beaulieu-Laroche, E.H.S. Toloza, M.-S. van der Goes, M. Lafourcade, D. Barnagian, Z.M. Williams, E.N. Eskandar, M.P. Frosch, S.S. Cash, and M.T. Harnett652 ➥ Cyclic-Nucleotide-and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Galion Cells ➥ by Z. Jiang, W.W.S. Yue, L. Chen, Y. Sheng, and K-W. Yau665 ➥ A Neural Circuit for Gut-Induced Reward ➥ by W. Han, L.A. Tellez, M.H. Perkins, I.O. Perez, T. Qu, J. Ferreira, T.L. Ferreira, D. Quinn, Z.-W. Liu, X.-B. Gao, M.M. Kaelberer, D.V. Bohorquez, S.J. Shammah-Lagnado, G. de Lartigue, and I.E. de Araujo679 ➥ Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer ➥ by V. Singh, B.S. Yeoh, B. Chassaing, X. Xiao, P. Saha, R. Aguilera Olvera, J.D. Lapek, Jr., L. Zhang, W.-B. Wang, S. Hao, M.D. Flythe, D.J. Gonzalez, P.D. Cani, J.R. Conejo-Garcia, N. Xiong, M.J. Kennett, B. Joe, A.D. Patterson, A.T. Gewirtz, and M. Vijay-Kumar695 ➥ An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State ➥ by C. Crewe, N. Joffin, J.M. Rutkowski, M. Kim, F. Zhang, D.A. Towler, R. Gordillo, and P.E. Scherer709 ➥ Integration of Parallel Opposing Memories Underlies Memory Extinction ➥ by J. Felsenberg, P.F. Jacob, T. Walker, O. Barnstedt, A.J. Edmondson-Stait, M.W. Pleizier, N. Otto, P. Schlegel, N. Sharifi, E. Perisse, C.S. Smith, J.S. Lauritzen, M. Costa, G.S.X.E. Jefferis, D.D. Bock, and S. Waddell723 ➥ The Basolateral Amygdala Is Essential for Rapid Escape: A Human and Rodent Study ➥ by D. Terburg, D. Scheggia, R. Triana del Rio, F. Klumpers, A.C. Ciobanu, B. Morgan, E.R. Montoya, P.A. Bos, G. Giobellina, E.H. van den Burg, B. de Gelder, D.J. Stein, R. Stoop, and J. van Honk736 ➥ A Map-like Micro-Organization of Grid Cells in the Medial Entorhinal Cortex ➥ by Y. Gu, S. Lewallen, A.A. Kinkhabwala, C. Domnisoru, K. Yoon, J.L. Gauthier, I.R. Fiete, and D.W. Tank751 ➥ Evolution of Metastases in Space and Time under Immune Selection ➥ by M. Angelova, B. Mlecnik, A. Vasaturo, G. Bindea, T. Fredriksen, L. Lafontaine, B. Buttard, E. Morgand, D. Bruni, A. Jouret-Mourin, C. Hubert, A. Kartheuser, Y. Humblet, M. Ceccarelli, N. Syed, F.M. Marincola, D. Bedognetti, M. Van den Eynde, and J. Galon766 ➥ Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy ➥ by K. Liang, E.R. Smith, Y. Aoi, K.L. Stoltz, H. Katagi, A.R. Woodfin, E.J. Rendleman, S.A. Marshall, D.C. Murray, L. Wang, P.A. Ozark, R.K. Mishra, R. Hashizume, G.E. Schiltz, and A. Shilatifard780 ➥ Centromeres License the Mitotic Condensation of Yeast Chromosome Arms ➥ by T. Kruitwagen, P. Chymkowitch, A. Denoth-Lippuner, J. Enserink, and Y. Barral.796 ➥ Determinants of Polar versus Nematic Organization in Networks of Dynamic Microtubules and Mitotic Motors ➥ by J. Roostalu, J. Rickman, C. Thomas, F. Nedelec, and T. Surrey809 ➥ Protein AMPylation by an Evolutionarily Conserved Pseudokinase ➥ by A. Sreelatha, S.S. Yee, V.A. Lopez, B.C. Park, L.N. Kinch, S. Pilch, K.A. Servage, J. Zhang, J. Jiou, M. Karasiewicz-Urbanska, M. Lobocka, N.V. Grishin, K. Orth, R. Kucharczyk, K. Pawlowski, D.R. Tomchick, and V.S. Tagliabracci822 ➥ Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis ➥ by Z. Chen, H. Suzuki, Y. Kobayashi, A.C. Wang, F. DiMaio, S.A> Kawashima, T. Walz, and T.M. Kapoor■ ■ THEORIES ■ ■ 835 ➥ Diverse Spatial Expression Patterns Emerge from Unified Kinetics of Transcriptional Bursting ➥ by B. Zoller, S.C. Little, and T. Gregor 848 ➥ Statistical Detection of Relatives Typed with Disjoint Forensic and Biometical Loci ➥ by J. Kim, M.D. Edge, B.F.B. Algee-Hewitt, J.Z. Li, and N.A. Rosenberg■ ■ RESOURCES ■ ■ 859 ➥ In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level ➥ by K. McDole, L. Guignard, F. Amat, A. Berger, G. Malandain, L.A. Royer, S.C. Turaga, K. Branson, and P.J. Keller877 ➥ Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control ➥ by P. Harrigan, H.D. Madhani, and H. El-Samad ■ ■ CORRECTIONS ■ ■ 887 ➥ A Neural Circuit for Gut-Induced Reward ➥ by W. Han, L.A. Tellez, M.H. Perkins, I.O. Perez, T. Qu, J. Ferreira, T.L. Ferreira, D. Quinn, Z.-W. Liu, X.-B. Gao, M.M. Kaelberer, D.V. Bohorquez, S.J. Shammah-Lagnado, G. de Lartigue, and I.E. de Araujo889 ➥ Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer ➥ by D.A. Quigley, H.X. Dang, S.G. Zhao, P. Lloyd, R. Aggarwal, J.J. Alumkal, A. Foye, V. Kothari, M.D. Perry, A.M. Bailey, D. Playdle, T.J. Barnard, L. Zhang, J. Zhang, J.F. Youngren, M.P. Cieslik, A. Parolia, T.M. Beer, G. Thomas, K.N. Chi, M. Gleave, N.A. Lack, A Zoubeidi, R.E. Reiter, M.B. Rettig, O. Witte, C.J. Ryan, L. Fong, W. Kim, T. Friedlander, J. Chou, H. Li, R. Das, H. Li, R. Moussavi-Baygi, H. Goodarzi, L.A. Gilbert, P.N. Lara, Jr., C.P. Evans, T.C. Goldstein, J.M. Stuart, S.A. Tomlins, D.E. Spratt, R.K. Cheetham, D.T. Cheng, K. Farh, J.S. Gehring, J. Hakenberg, A. Liao, P.G. Febbo, J. Shon, B. Sickler, S. Batzoglou, K.E. Knudsen, H.H. He, J. Huang, A.W. Wyatt, S.M. Dehm, A. Ashworth, A.M. Chinnaiyan, C.A. Maher, E.J. Small, and F.Y. Feng■ ■ ANNOUNCEMENTS ■ ■ ■ ■ POSITIONS AVALABLE ■ ■ ■ ■ ON THE COVER ■ ■ ➥ Mouse embryogenesis is a complex developmental process that is difficult to fully investigate and visualize over extended time scales. In this issue, McDole et al. (859-876) combine light-sheet microscopy with a computational framework to preserve multiple data dimensions and track cellular dynamics over the course of tissue morphogenesis. The cover image is a primarily artistic representation of a single time point during post-implantation mouse development generated by combined cell track, fat map, and image data.Origin: Cambridge, Massachusetts (MA) Country: Printed in the USA / United States / U.S.A. Condition: Like New! We Accept Offers!
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Publication Month: October
Publication Year: 2018
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Publication Frequency: Biweekly
Issue Number: 3
Volume: 175
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