Basic Principles of Drug Discovery and Development 2nd Edition by Benjamin E. Bl

Description: FREE SHIPPING UK WIDE Basic Principles of Drug Discovery and Development by Benjamin E. Blass Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics.Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborators fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientists early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. FORMAT Paperback LANGUAGE English CONDITION Brand New Author Biography As an industrial medicinal chemist, Dr. Blass has experience with major pharmaceutical organizations (Wyeth, Procter & Gamble Pharmaceuticals) and small biotech operations (Fox Chase Chemical Diversity Center), which provided him with a wealth of expertise in the art of drug discovery and development (including a wide range of disease states and biological targets). His position with Temple Universitys School of Pharmacy and the Moulder Center for Drug Discovery has provided him with essential experience as an educator and academic scientist. These experiences, as well as his training and expertise as a registered US patent agent, have provided him with the tools and skills necessary to bridge the gap between industrial drug discovery and academic research. Table of Contents 1. Drug Discovery and Development: An Overview of Modern Methods and Principles 2. The Drug Discovery Process: From Ancient Times to the Present Day 3. Classical Targets in Drug Discovery 4. In Vitro Screening Systems 5. Medicinal Chemistry 6. In vitro ADME and In vivo Pharmacokinetics 7. Animal Models of Disease States 8. Safety and Toxicology 9. Antibody Drug Discovery 10. Basics of Clinical Trials 11. Translational Medicine and Biomarkers 12. Organizational Considerations and Trends in the Pharmaceutical Industry 13. Intellectual Property and Patents in Drug Discovery 14. Case Studies in Drug Discovery Feature Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry Details ISBN0128172142 Language English Edition 2nd ISBN-10 0128172142 ISBN-13 9780128172148 Format Paperback Year 2021 Textbook 1 Place of Publication San Diego Country of Publication United States US Release Date 2021-06-30 UK Release Date 2021-06-30 Edition Description 2nd edition Replaces 9780124115088 Replaced by 9780443157479 Alternative 9780128172155 Author Benjamin E. Blass Pages 712 Publisher Elsevier Science Publishing Co Inc Publication Date 2021-06-30 Imprint Academic Press Inc DEWEY 615.19 Audience Tertiary & Higher Education NZ Release Date 2021-04-18 AU Release Date 2021-04-18 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! 30 DAY RETURN POLICY No questions asked, 30 day returns! FREE DELIVERY No matter where you are in the UK, delivery is free. SECURE PAYMENT Peace of mind by paying through PayPal and eBay Buyer Protection TheNile_Item_ID:132384032;

Price: 158.06 GBP

Location: London

End Time: 2024-12-26T03:08:52.000Z

Shipping Cost: 10.5 GBP